2.1.4 Purpose of research - Revision history

Bjoerngerlach: /* B. Guidance & Expectations */

2024-10-13T09:52:00Z

‎B. Guidance & Expectations

Bjoerngerlach: /* B. Guidance & Expectations */

2024-10-13T09:51:11Z

‎B. Guidance & Expectations

Bjoerngerlach: /* B. Guidance & Expectations */

2024-10-13T09:50:54Z

‎B. Guidance & Expectations

Bjoerngerlach: /* B. Guidance & Expectations */

2021-12-15T16:53:17Z

‎B. Guidance & Expectations

Bjoerngerlach: /* C. Resources */

2021-09-01T14:44:07Z

‎C. Resources

Bjoerngerlach: /* B. Guidance & Expectations */

2021-03-30T10:43:01Z

‎B. Guidance & Expectations

ChristophEmmerich at 12:56, 24 March 2021

2021-03-24T12:56:14Z

ChristophEmmerich at 12:51, 24 March 2021

2021-03-24T12:51:41Z

ChristophEmmerich at 12:45, 24 March 2021

2021-03-24T12:45:28Z

ChristophEmmerich at 12:44, 24 March 2021

2021-03-24T12:44:07Z

← Older revision		Revision as of 09:52, 13 October 2024
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−	* Please refer to [[Glossary]] for explanation on the EQIPD use of the verbs "must" and "should"	+	* * Please refer to [[Glossary]] for explanation on the EQIPD use of the verbs "must" and "should"

← Older revision		Revision as of 09:51, 13 October 2024
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−	* * Please refer to [[Glossary]] for explanation on the EQIPD use of the verbs "must" and "should"	+	* Please refer to [[Glossary]] for explanation on the EQIPD use of the verbs "must" and "should"

← Older revision		Revision as of 09:50, 13 October 2024
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	\|}		\|}

−	* Please refer to [[Glossary]] for explanation on the EQIPD use of the verbs "must" and "should"	+	* * Please refer to [[Glossary]] for explanation on the EQIPD use of the verbs "must" and "should"

@@ Line 29: / Line 29: @@
 {| class="wikitable"
+|
-|'''All research'''
+|'''Research NOT informing a formal knowledge claim'''
 |'''Research informing a formal knowledge claim (i.e. research requiring maximal rigor)*'''
 |-

← Older revision		Revision as of 14:44, 1 September 2021
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	== C. Resources ==		== C. Resources ==
−	Template to create a study protocol based on the above guidance - [https://paasp.sharepoint.com/:w:/s/EQIPD/~~Ecmg1s58CM1Nssq_Wv3~~-~~Ei8BfcCMqxgQcRzesGy9a5gdRg~~?e=~~Nc8dHL~~ 2.1.1 Study protocol.docx], [https://paasp.sharepoint.com/:w:/s/EQIPD/~~ETydIHKmJ1ZEt6EC87dtn9AB9RP3u29lxF0Omb-Ugesh1Q~~?e=~~Frbycd~~ 2.1.1 Study protocol with macro.docm]	+	Template to create a study protocol based on the above guidance - [https://paasp.sharepoint.com/:w:/s/EQIPD/EbuGPqIAiTtKlmRQJ7bSy_0BfmYNqXl-W6Reh3tW5vAIzQ?e=CkXHXv 2.1.1 Study protocol.docx], [https://paasp.sharepoint.com/:w:/s/EQIPD/EXmh9e3w78ZLqPjOd1WNdaQBpt4FZ0mTctaQCRTM8NisMw?e=UJrcmw 2.1.1 Study protocol with macro.docm]

← Older revision		Revision as of 10:43, 30 March 2021
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	To consider adding this subject to a training program for new employees or refresher training (if appropriate)		To consider adding this subject to a training program for new employees or refresher training (if appropriate)
−

	== C. Resources ==		== C. Resources ==

@@ Line 32: / Line 32: @@
 |'''Research informing a formal knowledge claim (i.e. research requiring maximal rigor)*'''
 |-
-|'''[[2.1.1 Study (experimental) plan|Study (experimental) plan]]'''
+|'''[[2.1.1 Study protocol|Study protocol]]'''
 |should be defined and documented before starting the experiments
 |must be defined and documented before starting the experiments
@@ Line 79: / Line 79: @@
 == C. Resources ==
-Template to create a study protocol based on the above guidance  - [https://paasp.sharepoint.com/:w:/s/EQIPD/Ecmg1s58CM1Nssq_Wv3-Ei8BfcCMqxgQcRzesGy9a5gdRg?e=Nc8dHL 2.1.1 Study plan.docx], [https://paasp.sharepoint.com/:w:/s/EQIPD/ETydIHKmJ1ZEt6EC87dtn9AB9RP3u29lxF0Omb-Ugesh1Q?e=Frbycd 2.1.1 Study plan with macro.docm]
+Template to create a study protocol based on the above guidance  - [https://paasp.sharepoint.com/:w:/s/EQIPD/Ecmg1s58CM1Nssq_Wv3-Ei8BfcCMqxgQcRzesGy9a5gdRg?e=Nc8dHL 2.1.1 Study protocol.docx], [https://paasp.sharepoint.com/:w:/s/EQIPD/ETydIHKmJ1ZEt6EC87dtn9AB9RP3u29lxF0Omb-Ugesh1Q?e=Frbycd 2.1.1 Study protocol with macro.docm]

@@ Line 20: / Line 20: @@
 == B. Guidance & Expectations ==
-One of the [[Core Requirements]] of the EQIPD Quality System is that investigators must assert in advance whether a study will be conducted to inform a formal knowledge claim. This statement should be recorded in the [[2.1.1 Study (experimental) plan]] (see below for a template).
+One of the [[Core Requirements]] of the EQIPD Quality System is that investigators must assert in advance whether a study will be conducted to inform a formal knowledge claim. This statement should be recorded in the [[2.1.1 Study protocol]] (see below for a template).
 If uncertain about your study being knowledge-claiming or not, please check [[FAQ]] page or contact the EQIPD Expert Team for an advice.

@@ Line 50: / Line 50: @@
 |'''[[2.1.6 Sample size and power analysis|Sample size and power analysis]]'''
 |advised to define and document before starting the experiments
-|must be defined and documented before starting the experiments (e.g. included in the study plan)
+|must be defined and documented before starting the experiments (e.g. included in the study protocol)
 |-
 |'''[[2.3.3 Statistical analysis|Data analysis]]'''
 |advised to define and document before starting the experiments
-|must be defined and documented before starting the experiments (e.g. as a formal statistical analysis plan and/or included in the study plan)
+|must be defined and documented before starting the experiments (e.g. as a formal statistical analysis plan and/or included in the study protocol)
 |-
 |'''[[2.1.9 Inclusion and exclusion criteria|Inclusion and exclusion criteria]]'''
 |advised to define and document before starting the experiments
-|must be defined and documented before starting the experiments (e.g. included in the study plan)
+|must be defined and documented before starting the experiments (e.g. included in the study protocol)
 |-
-|'''Deviations from study (experimental) plan'''
+|'''Deviations from study protocol'''
 |advised to document
 |must be documented
@@ Line 79: / Line 79: @@
 == C. Resources ==
-Template to create a study (experimental) plan based on the above guidance  - [https://paasp.sharepoint.com/:w:/s/EQIPD/Ecmg1s58CM1Nssq_Wv3-Ei8BfcCMqxgQcRzesGy9a5gdRg?e=Nc8dHL 2.1.1 Study plan.docx], [https://paasp.sharepoint.com/:w:/s/EQIPD/ETydIHKmJ1ZEt6EC87dtn9AB9RP3u29lxF0Omb-Ugesh1Q?e=Frbycd 2.1.1 Study plan with macro.docm]
+Template to create a study protocol based on the above guidance  - [https://paasp.sharepoint.com/:w:/s/EQIPD/Ecmg1s58CM1Nssq_Wv3-Ei8BfcCMqxgQcRzesGy9a5gdRg?e=Nc8dHL 2.1.1 Study plan.docx], [https://paasp.sharepoint.com/:w:/s/EQIPD/ETydIHKmJ1ZEt6EC87dtn9AB9RP3u29lxF0Omb-Ugesh1Q?e=Frbycd 2.1.1 Study plan with macro.docm]

@@ Line 10: / Line 10: @@
 For every study, EQIPD recommends scientists to apply protection against risks of bias and to be transparent about the protective measures applied.
-EQIPD requires that the maximal rigor possible is applied (and exceptions explained / documented in the study plan) to research that is conducted with the prior intention of informing a knowledge claim ([[Glossary]]). This will usually (but not always) involve some form of null hypothesis statistical testing or formal Bayesian analysis. Hypotheses are articulated in advance of data collection, with pre-specified criteria defining the primary outcome measure and the statistical test to be used. Depending on the purpose for which the knowledge claim will be used, different research strategies are appropriate. A single well conducted preclinical study may be considered sufficient to convince others that the phenomena are real enough to justify their attention, but may not be sufficient to justify major research investment such as a clinical study.
+EQIPD requires that the maximal rigor possible is applied (and exceptions explained / documented in the study protocol) to research that is conducted with the prior intention of informing a knowledge claim ([[Glossary]]). This will usually (but not always) involve some form of null hypothesis statistical testing or formal Bayesian analysis. Hypotheses are articulated in advance of data collection, with pre-specified criteria defining the primary outcome measure and the statistical test to be used. Depending on the purpose for which the knowledge claim will be used, different research strategies are appropriate. A single well conducted preclinical study may be considered sufficient to convince others that the phenomena are real enough to justify their attention, but may not be sufficient to justify major research investment such as a clinical study.
 Examples of research requiring the maximal rigor possible include:

2.1.4 Purpose of research - Revision history

Bjoerngerlach: /* ​B. Guidance & Expectations */

Bjoerngerlach: /* ​B. Guidance & Expectations */

Bjoerngerlach: /* ​B. Guidance & Expectations */

Bjoerngerlach: /* ​B. Guidance & Expectations */

Bjoerngerlach: /* C. Resources */

Bjoerngerlach: /* ​B. Guidance & Expectations */

ChristophEmmerich at 12:56, 24 March 2021

ChristophEmmerich at 12:51, 24 March 2021

ChristophEmmerich at 12:45, 24 March 2021

ChristophEmmerich at 12:44, 24 March 2021

Bjoerngerlach: /* B. Guidance & Expectations */

Bjoerngerlach: /* B. Guidance & Expectations */

Bjoerngerlach: /* B. Guidance & Expectations */

Bjoerngerlach: /* B. Guidance & Expectations */

Bjoerngerlach: /* B. Guidance & Expectations */