PREPARE - Revision history

AdrianSmith: Added link to PREPARE

2020-10-02T14:42:54Z

Added link to PREPARE

Bjoerngerlach at 14:18, 2 October 2020

2020-10-02T14:18:08Z

Bjoerngerlach at 14:10, 2 October 2020

2020-10-02T14:10:05Z

87.191.22.234 at 14:08, 2 October 2020

2020-10-02T14:08:24Z

87.191.22.234 at 14:07, 2 October 2020

2020-10-02T14:07:56Z

Bjoerngerlach at 10:45, 29 September 2020

2020-09-29T10:45:07Z

AdrianSmith at 10:02, 29 September 2020

2020-09-29T10:02:09Z

AdrianSmith at 09:59, 29 September 2020

2020-09-29T09:59:00Z

Bjoerngerlach at 09:34, 29 September 2020

2020-09-29T09:34:43Z

AdrianSmith at 08:58, 29 September 2020

2020-09-29T08:58:21Z

@@ Line 118: / Line 118: @@
 == C. Resources ==
-Information on this and related pages is based on or copied directly from the PREPARE guidelines:
+Information on this and related pages is based on or copied directly from [https://norecopa.no/prepare the PREPARE guidelines]:
 * Smith, AJ, Clutton, RE, Lilley, E, Hansen KEAa, Brattelid, T. (2018): PREPARE: Guidelines for planning animal research and testing. Laboratory Animals, 52(2): 135-141. DOI: 10.1177/0023677217724823 [https://journals.sagepub.com/doi/full/10.1177/0023677217724823]

@@ Line 122: / Line 122: @@
 Link to the file "EQIPD external NEED PREPARE.xlsx" for import into the Planning Tool [https://paasp.sharepoint.com/:x:/s/EQIPD/EfjG8KkiAO1Fsx5NsyxJ_t4B2e_Cn-P09M2bVoiS0EKBaQ?e=Urc7As]
 ----------------
 back to [[Toolbox]]

@@ Line 121: / Line 121: @@
 * Smith, AJ, Clutton, RE, Lilley, E, Hansen KEAa, Brattelid, T. (2018): PREPARE: Guidelines for planning animal research and testing. Laboratory Animals, 52(2): 135-141. DOI: 10.1177/0023677217724823 [https://journals.sagepub.com/doi/full/10.1177/0023677217724823]
-Link to the file "EQIPD external NEED PREPARE.xlsx" for import into the Planning Tool [https://paasp.sharepoint.com/:f:/s/EQIPD/EhZf0M1a1mhDigOA0JqP1psBtghFaKUTWV_HHyolYzLQeg?e=FzAIb7]
+Link to the file "EQIPD external NEED PREPARE.xlsx" for import into the Planning Tool [https://paasp.sharepoint.com/:x:/s/EQIPD/EfjG8KkiAO1Fsx5NsyxJ_t4B2e_Cn-P09M2bVoiS0EKBaQ?e=Urc7As]
 ----------------
 back to [[Toolbox]]

@@ Line 119: / Line 119: @@
 == C. Resources ==
 Information on this and related pages is based on or copied directly from the PREPARE guidelines:
+* Smith, AJ, Clutton, RE, Lilley, E, Hansen KEAa, Brattelid, T. (2018): PREPARE: Guidelines for planning animal research and testing. Laboratory Animals, 52(2): 135-141. DOI: 10.1177/0023677217724823 [https://journals.sagepub.com/doi/full/10.1177/0023677217724823]
 Link to the file "EQIPD external NEED PREPARE.xlsx" for import into the Planning Tool [https://paasp.sharepoint.com/:f:/s/EQIPD/EhZf0M1a1mhDigOA0JqP1psBtghFaKUTWV_HHyolYzLQeg?e=FzAIb7]

@@ Line 122: / Line 122: @@
 Smith, AJ, Clutton, RE, Lilley, E, Hansen KEAa, Brattelid, T. (2018): PREPARE: Guidelines for planning animal research and testing. Laboratory Animals, 52(2): 135-141. DOI: 10.1177/0023677217724823 [https://journals.sagepub.com/doi/full/10.1177/0023677217724823]
+Link to the file "EQIPD external NEED PREPARE.xlsx" for import into the Planning Tool [https://paasp.sharepoint.com/:f:/s/EQIPD/EhZf0M1a1mhDigOA0JqP1psBtghFaKUTWV_HHyolYzLQeg?e=FzAIb7]
 ----------------
 back to [[Toolbox]]

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 == A. Background ==
 Reproducible science requires careful planning, to consider all the factors which may introduce variability in the recorded data. In the case of in vivo studies, this should be done in close collaboration with the animal care staff. The [https://norecopa.no/prepare PREPARE guidelines] were developed over a 30-year period, based upon the authors' experiences in planning and supervising animal research, and managing accredited animal facilities.
@@ Line 7: / Line 5: @@
 PREPARE consists of [https://norecopa.no/PREPARE/prepare-checklist a 2-page checklist], in over 20 languages, of 15 main topics. The topics cover the three broad areas which determine the quality of the preparation for animal studies:
-. Formulation of the study
+# Formulation of the study
-. Dialogue between scientists and the animal facility
+# Dialogue between scientists and the animal facility
-. Quality control of the components in the study
+# Quality control of the components in the study
 The checklist is supported by [https://norecopa.no/PREPARE a comprehensive website], with sections for each topic, where more information is provided, including links to quality guidelines from around the world, and key scientific papers on the subject. The website is updated continuously.

← Older revision		Revision as of 09:34, 29 September 2020
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	The PREPARE checklist can be adapted to meet special needs, such as field studies.		The PREPARE checklist can be adapted to meet special needs, such as field studies.

−	The PREPARE planning guidelines are complementary to reporting guidelines such as [[ARRIVE]] and [https://norecopa.no/3r-guide/gold-standard-publication-checklist-gspc GSPC]. They are a dynamic set which will evolve as more species- and situation-specific guidelines are produced, and as best practice within Laboratory Animal Science progresses.	+	The PREPARE planning guidelines are complementary to reporting guidelines such as [[ARRIVE 2.0]] and [https://norecopa.no/3r-guide/gold-standard-publication-checklist-gspc GSPC]. They are a dynamic set which will evolve as more species- and situation-specific guidelines are produced, and as best practice within Laboratory Animal Science progresses.

@@ Line 30: / Line 30: @@
 |-
-|[[https://norecopa.no/prepare/2-legal-issues 2. Legal issues]]
+|[https://norecopa.no/prepare/2-legal-issues 2. Legal issues]
 |Consider how the research is affected by relevant legislation for animal research and other areas, e.g. animal transport, occupational health and safety.
 Locate relevant guidance documents (e.g. EU guidance on project evaluation).
 |-
-|[[https://norecopa.no/prepare/3-ethical-issues-harm-benefit-assessment-and-humane-endpoints 3. Ethical issues, Harm-Benefit Assessment and humane endpoints]]
+|[https://norecopa.no/prepare/3-ethical-issues-harm-benefit-assessment-and-humane-endpoints 3. Ethical issues, Harm-Benefit Assessment and humane endpoints]
 |Construct a lay summary.
 In dialogue with ethics committees, consider whether statements about this type of research have already been produced.
@@ Line 47: / Line 47: @@
 |-
-|[[https://norecopa.no/prepare/4-experimental-design-and-statistical-analysis 4. Experimental design and statistical analysis]]
+|[https://norecopa.no/prepare/4-experimental-design-and-statistical-analysis 4. Experimental design and statistical analysis]
 |Consider pilot studies, statistical power and significance levels.
 Define the experimental unit and decide upon animal numbers.
@@ Line 53: / Line 53: @@
 |-
-|[[https://norecopa.no/prepare/5-objectives-and-timescale-funding-and-division-of-labour 5. Objectives and timescale, funding and division of labour]]
+|[https://norecopa.no/prepare/5-objectives-and-timescale-funding-and-division-of-labour 5. Objectives and timescale, funding and division of labour]
 |Arrange meetings with all relevant staff when early plans for the project exist.
 Construct an approximate timescale for the project, indicating the need for assistance with preparation, animal care, procedures and waste disposal/decontamination.
@@ Line 60: / Line 60: @@
 |-
-|[[https://norecopa.no/prepare/6-facility-evaluation 6. Facility Evaluation]]
+|[https://norecopa.no/prepare/6-facility-evaluation 6. Facility Evaluation]
 |Conduct a physical inspection of the facilities, to evaluate building and equipment standards and needs.
 Discuss staffing levels at times of extra risk.
 |-
-|[[https://norecopa.no/prepare/7-education-and-training 7. Education and training]]
+|[https://norecopa.no/prepare/7-education-and-training 7. Education and training]
 |Assess the current competence of staff members and the need for further education or training prior to the study.
 |-
-|[[https://norecopa.no/prepare/8-health-risks-waste-disposal-and-decontamination 8. Health risks, waste disposal and decontamination]]
+|[https://norecopa.no/prepare/8-health-risks-waste-disposal-and-decontamination 8. Health risks, waste disposal and decontamination]
 |Perform a risk assessment, in collaboration with the animal facility, for all persons and animals affected directly or indirectly by the study.
 Assess, and if necessary produce, specific guidance for all stages of the project.
@@ Line 75: / Line 75: @@
 |-
-|[[https://norecopa.no/prepare/9-test-substances-and-procedures 9. Test substances and procedures]]
+|[https://norecopa.no/prepare/9-test-substances-and-procedures 9. Test substances and procedures]
 |Provide as much information as possible about test substances.
 Consider the feasibility and validity of test procedures and the skills needed to perform them.
 |-
-|[[https://norecopa.no/prepare/10-experimental-animals 10. Experimental animals]]
+|[https://norecopa.no/prepare/10-experimental-animals 10. Experimental animals]
 |Decide upon the characteristics of the animals that are essential for the study and for reporting.
 Avoid generation of surplus animals.
 |-
-|[[https://norecopa.no/prepare/11-quarantine-and-health-monitoring 11. Quarantine and health monitoring]]
+|[https://norecopa.no/prepare/11-quarantine-and-health-monitoring 11. Quarantine and health monitoring]
 |Discuss the animals’ likely health status, any needs for transport, quarantine and isolation, health monitoring and consequences for the personnel.
 |-
-|[[https://norecopa.no/prepare/12-housing-and-husbandry 12. Housing and husbandry]]
+|[https://norecopa.no/prepare/12-housing-and-husbandry 12. Housing and husbandry]
 |Attend to the animals’ specific instincts and needs, in collaboration with expert staff.
 Discuss acclimation, optimal housing conditions and procedures, environmental factors and any
@@ Line 95: / Line 95: @@
 |-
-|[[https://norecopa.no/prepare/13-experimental-procedures 13. Experimental procedures]]
+|[https://norecopa.no/prepare/13-experimental-procedures 13. Experimental procedures]
 |Develop refined procedures for capture, immobilisation, marking, and release or re-homing.
 Develop refined procedures for substance administration, sampling, sedation and anaesthesia, surgery and other techniques.
 |-
-|[[https://norecopa.no/prepare/14-humane-killing-release-re-use-or-re-homing 14. Humane killing, release, re-use or re-homing]]
+|[https://norecopa.no/prepare/14-humane-killing-release-re-use-or-re-homing 14. Humane killing, release, re-use or re-homing]
 |Consult relevant legislation and guidelines well in advance of the study.
 Define primary and emergency methods for humane killing.
@@ Line 106: / Line 106: @@
 |-
-|[[https://norecopa.no/prepare/15-necropsy 15. Necropsy]]
+|[https://norecopa.no/prepare/15-necropsy 15. Necropsy]
 |Construct a systematic plan for all stages of necropsy, including location, and identification of all animals and samples.